POS1289 ANALYSIS OF INFECTIOUS SPONDYLODISCITIS: FIVE-YEARS DATA

Background Spondylodiscitis (SD) is an infection of the vertebral body or disc and may also extend to epidural space, posterior elements, paraspinal soft tissues. It a cause morbidity mortality. However, diagnosis often delayed because non-specific clinical features. Objectives In this study, we aimed describe diagnostic features infectious SD Methods We conducted retrospective study including 40 cases SD, performed over period five years (2014-2019). Epidemiological, characteristics, laboratory results imaging findings were uniformly collected. Results : Of patients, 37.3% male. The mean age was 53.3 ± 13.9 [28-83] median Charlson Comorbidity Index 1. Advanced age, tuberculosis brucellar contagion predominant risk factors. duration from onset 41 days [8-300]. Low back pain (LBP) most common symptom (98%). Lumbar spine frequent location (71%). Seven patients had contiguous multiple levels (>2 bodies). Neurologic symptoms (radicular pain, spinal chord compression, neurologic loss) observed in 15 patients. erythrocyte sedimentation rate 54 mm/1st h [13-223], CRP 26.3 mg/L [7-387]. Leukopenia (<4000 WBCs/mm3) found three (9.8%). Magnetic resonance confirmed all cases, revealed epiduritis 17 (34.8%), paravertebral abscesses 11 (20.3%) cord compression 4 (7.8%). Pathogens isolated 19 cases. Computed tomography-guided percutaneous biopsy (PDB) 16 (53.5%) conclusive (11/15) (66.8%). Mycobacterium (MT) pathogene (46.4%) followed by Brucella (21.4%), Pyogenes (17.8%) Gram-negative bacteria (14.2%). One patient both MT Staphylococcus haemolyticus.Paravertebral abscess formation (19.6%) occurred frequently with tuberculous (P= 0.02). Leucocytosis (>10,000 significantly higher (p=0.002) than other types SD. All treated antibiotics only one underwent surgical act. outcome favourable 27 (86.8%). Conclusion should be considered for presenting chronic backpain especially when associated examination abnormalities. our spondylodiscitis frequent, which highlights fact that osteoarticular remains endemic developing countries, where it still constitutes major public health problem Disclosure Interests None declared